Amylin Pharmaceuticals Inc. could
potentially receive more than $1 billion from a partnership with Japan''s Takeda
Pharmaceutical Co. on potential weight-loss treatments, reports the Associated
Press. Amylin, which is based in San Diego, said it will receive $75 million
upfront from Takeda and said future payments for development and achieving
commercial milestones could top $1 billion. The deal includes two potential
weight-loss treatments, a pramlintide-metreleptin combination and davalintide.
Both potential drugs are in midstage, or Phase II, clinical development. The
deal also includes additional compounds from both companies research programs.
Aside from milestone payments, Amylin is also eligible for royalties on global sales.
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