Pfizer''s Lipitor has no effect on Alzheimer''s disease
April 21, 2008
According to the
Associated Press, drug developer Pfizer Inc. said recently that adding
its cholesterol drug Lipitor to the Alzheimer''s disease treatment
Aricept had no impact on Alzheimer''s patients.
The combination of 80 milligrams of
Lipitor with Eisai Co.''s Aricept neither improved nor worsened
cognition in the 18-month study of 640 patients. The drug combination
was compared with a regimen of Aricept and placebo.
The study results were presented at the annual American Academy of Neurology meeting in Chicago.
Lipitor is the world''s best selling
drug and Pfizer''s biggest revenue driver. Its patent will expire in
2010, opening the door for generic competition and possibly cutting
billions of dollars annually in revenue for Pfizer.
Sales of the drug are already on the decline, shedding 7 percent to reach $3.14 billion in the first quarter.